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. 2022 Jul 6;5(7):e2219672. doi: 10.1001/jamanetworkopen.2022.19672

Table 3. Dementia Risk Factor Prevalences and Population Attributable Fractions Among US Adults, Overall and by Race and Ethnicity.

Risk factor Total population Hispanic Non-Hispanic Asian Non-Hispanic Black Non-Hispanic White
Prevalence, % PAF, % (95% CI) Prevalence, % PAF, % (95% CI) Prevalence, % PAF, % (95% CI) Prevalence, % PAF, % (95% CI) Prevalence, % PAF, % (95% CI)
Less education 10.7 6.0 (2.7-9.8) 27.1 14.0% (6.6-21.5) 6.4 3.7 (1.6-6.1) 10.6 6.0% (2.7-9.7) 5.5 3.2 (1.4-5.3)
Hearing loss 10.8 8.9 (3.9-15.7) 13.1 10.5 (4.7-18.5) 6.9 5.8 (2.6-10.7) 6.5 5.5 (2.4-10.1) 10.6 8.7 (3.9-15.7)
TBI 17.1 12.0 (8.5-17.0) 10.3 7.6 (5.3-11.0) 6.0 4.6 (3.1-6.7) 9.2 6.9 (4.7-9.9) 20.1 13.9 (9.8-19.4)
Hypertension 42.2 20.2 (6.3-34.4) 38.5 18.8 (5.8-32.3) 38.5 18.8 (5.8-32.3) 61.0 26.8 (8.9-43.1) 39.8 19.3 (6.0-33.0)
Excessive alcohol 3.6 0.7 (0.2-1.1) 2.0 0.4 (0.1-0.6) 0.7 0.1 (0.0-0.2) 2.7 0.5 (0.2-0.8) 4.2 0.8 (0.3-1.3)
Obesity 44.0 20.9 (13.0-28.8) 48.3 22.5 (14.1-30.8) 14.6 8.1 (4.7-11.8) 54.3 24.6 (15.6-33.3) 43.5 20.7 (12.9-28.6)
Smoking 8.5 4.9 (1.3-9.3) 6.9 4.0 (1.0-7.6) 4.9 2.9 (0.7-5.6) 11.7 6.6 (1.7-12.3) 8.4 4.8 (1.1-9.2)
Depression 7.4 6.2 (3.9-9.0) 10.7 8.8 (5.6-12.5) 4.3 3.7 (2.3-5.4) 6.6 5.6 (3.5-8.1) 7.2 6.1 (3.8-8.7)
Social isolation 11.9 6.7 (3.7-9.2) 24.0 12.6 (7.1-16.9) 8.0 4.6 (2.5-6.4) 12.1 6.8 (3.7-9.3) 10.8 6.1 (3.3-8.4)
Physical inactivity 62.8 20.1 (9.1-29.6) 68.6 21.5 (9.9-31.5) 56.6 18.5 (8.3-27.5) 73.2 22.6 (10.5-32.9) 61.3 19.7 (8.9-29.1)
Diabetes 28.6 12.5 (8.6-18.4) 41.0 17.0 (11.9-24.5) 44.1 18.1 (12.7-25.8) 37.2 15.7 (10.9-22.7) 25.4 11.3 (7.7-16.7)
Air pollution 22.8 2.2 (1.6-2.4) 44.4 4.3 (3.0-4.7) 55.2 5.2 (3.7-5.7) 41.3 4.0 (2.8-4.3) 17.2 1.7 (1.2-1.9)
Combined factorsa NA 41.0 (22.7-55.9) NA 46.7 (27.3-61.5) NA 35.8 (19.5-49.9) NA 45.6 (25.7-60.5) NA 39.4 (22.7-55.9)

Abbreviations: NA, not applicable; PAF, population attributable fraction; TBI, traumatic brain injury.

a

Combined PAF estimate is weighted by risk factor communality. See Methods section for details.