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. 2022 Jun 23;16:938674. doi: 10.3389/fnins.2022.938674

TABLE 3.

Correlation coefficients between DTI parameters and histopathological parameters.

FA
RD
RS3-EPI RS5-EPI RS7-EPI RS3-EPI RS5-EPI RS7-EPI
POAA r = 0.851 (P = 0.007*) 0.911 (0.002*) 0.897 (0.003*) −0.816 (0.013*) −0.882 (0.004*) −0.691 (0.058)
POMA 0.799 (0.017*) 0.944 (<0.001*) 0.769 (0.026*) −0.764 (0.027*) −0.964 (<0.001*) −0.812 (0.014*)
TOM 0.751 (0.032*) 0.953 (<0.001*) 0.741 (0.036*) −0.808 (0.015*) −0.922 (<0.001*) −0.709 (0.049*)
DOMF 0.664 (0.073) 0.886 (0.003*) 0.623 (0.099) −0.765 (0.027*) −0.876 (0.004*) −0.716 (0.046*)

DTI, diffusion tensor imaging; FA, fractional anisotropy; RD, radial diffusivity. Histopathological parameters: POAA, percentage of axon area; POMA, percentage of myelin area; TOM, thickness of myelin; DOMF, diameter of myelinated fiber. r value, correlation coefficient value. P-value in parentheses, the result of correlation. *P ≤ 0.05.