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. 2022 Jun 22;6(6):e36521. doi: 10.2196/36521

Table 7.

Final combined mixed effects model predicting Patient Health Questionnaire (PHQ-8) score changea.


Estimate SE P value
Intercept 15.36 0.14 <.001
Week −1.10 0.04 <.001
Week2 0.06 0.002 <.001
Associate’s or bachelor’s degree or higher (ref=high school) −0.18 0.12 .120
Associate’s degree or higher × week (ref=high school) −0.07 0.02 .002
Age (years, ref=18-25)

26-35 −0.16 0.13 .20

36-49 −0.10 0.16 .52

>50 −0.41 0.26 .12
Age (years, ref=18-25) × week

26-35 −0.03 0.02 .15

36-49 −0.01 0.03 .76

>50 0.04 0.04 .32
Intake PHQ-8 score 3.73 0.06 <.001
Intake PHQ-8 score × week −0.50 0.03 <.001
Intake PHQ-8 score × week2 0.03 0.002 <.001
First time in therapy −0.07 0.13 .58
First time in therapy × week −0.30 0.06 <.001
First time in therapy × week2 0.03 0.005 <.001

aPredictor and predictor × time interaction variables that were significant in simpler models were included. The intake PHQ-8 scores were grand mean-centered.