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. 2022 Jul 4;15(7):100662. doi: 10.1016/j.waojou.2022.100662

Table 1.

Demographic and clinical characteristics of patients with controlled severe asthma (CSA) and uncontrolled severe asthma (UCSA).


Total
CSA
UCSA
P
M (Q1-Q3) M (Q1-Q3) M (Q1-Q3)
Age 55.5 (44.6–64.4) 55.5 (49.25–64.3) 57.5 (44.8–63.34) 0.74
BMI (kg/m2) 28.9 (25.7–32.5) 27.8 (25.7–31.3) 30.7 (25.6–33.8) 0.3
2018 n = 60 n = 37 n = 23
RR 17 (16–18) 16 (16–18.5) 18 (16.18) 0.36
HR (bpm) 76 (70–80) 75 (70–80) 76 (72–80) 0.26
2019 n = 60 n = 38 n = 22
RR 16 (16–18) 16 (16–18) 17 (16–18) 0.26
HR 72 (70.0–75.7) 71.5 (70.0–75.0) 73 (67.8–77.5) 0.74
2018 n = 40 n = 23 n = 17
FEV1 (%) 80.0 (68.3–91.8) 87.0 (71.0–93.0) 73.0 (59.50–82.50) 0.08
PEF (%) 88.0 (70.5–107.3) 102.0 (82.0–113.0) 76.0 (64.50–92.50) 0.005
n = 12 n = 6 n = 6
IgE (mg/dL) 606 (232–2153) 606 (324–2568) 730 (193–2863) 0.7
n = 22 n = 15 n = 7
Leukocytes, thousands/μL 6628 (8405–10245) 6530 (8370–9200) 6660 (10,080–11150) 0.36
Eosinophils, thousands/μL 175 (430.0–648.5) 160 (330.0–650.0) 260 (460–648) 0.6
Eosinophils ˃300, thousands/μL, n (%) 14 (63.6) 8 (53.3) 5 (71.4)
2019 n = 40 n = 23 n = 17
FEV1 83.0 (68.0–90.8) 83.0 (68.0–93.0) 83.0 (67.5–89.0) 0.58
PEF 92.0 (80.0–105.5) 92.0 (82.0–109.0) 93.0 (79.5–104.0) 0.68
n = 16 n = 10 n = 6
IgE 250 (172.0–440) 280 (131–490) 221 (160–502.5) 0.98
n = 24 n = 14 n = 10
Leukocytes 8505 (5725–10090) 8640 (5688–10338) 8190 (5698–10198) 0.83
Eosinophils 371 (205–565) 371 (258–693) 355 (168–468) 0.34
Eosinophils ˃ 300, n (%) 14 (58.3) 9 (64.3) 5 (50.0)

UCSA was defined by the presence of at least one exacerbation in the year; BMI, body mass index; RR, respiratory rate; HR, heart rate; P, p-value resulting from the Mann-Whitney test; Q1 and Q3, quartiles 1 and 3 respectively