Table 1. Predictive Performance of the 2021 European-SCORE2, US-PCE, UK-QRISK3, and European-SCORE1 Models.
| Risk model | Mean estimated 10-y ASCVD risk, % (95% CI) | P/O ratio | HL coefficienta | Harrel C statisticb | P value |
|---|---|---|---|---|---|
| European-SCORE2 | 4.2 (4.1-4.2) | 0.8 | 207 | 0.710 [Reference] | |
| US-PCE | 6.4 (6.4-6.5) | 1.3 | 442 | 0.712 | .004 |
| UK-QRISK3 | 7.4 (7.4-7.5) | 1.3 | 460 | 0.713 | .005 |
| European-SCORE1 | 2.1 (2.0-2.1) | 5.8 | 957 | 0.700 | <.001 |
Abbreviations: ASCVD, atherosclerotic cardiovascular disease; HL, Hosmer-Lemeshow; PCE, pooled cohort equations; P/O, predicted/observed ASCVD events; SCORE, Systematic Coronary Risk Evaluation.
a
For the Hosmer-Lemeshow goodness of fit, lower scores indicate better fit.
b
Discrimination (C statistic) for European-SCORE2 ASCVD end point.