Table 4.
Receiver operating characteristic curve analysis of quantitative DECT parameters for discriminating the different aggressiveness of OTSCC.
| Parameters | AUC (95%CI) | Threshold | Sensitivity (95%CI) | Specificity (95%CI) | Accuracy (%) |
|---|---|---|---|---|---|
| Pathologic stages | |||||
| λHu in VP | 0.80 (0.71,0.89) | 2.66 | 65.4 (50.9,78.0) | 87.8 (73.8,95.9) | 75.3 (65.2,83.6) |
| Histologic differentiation | |||||
| nIC in VP | 0.78 (0.69,0.88) | 0.46 | 75.9 (56.5,89.7) | 75.0 (62.6,85.0) | 75.3 (65.2,83.6) |
| Lymph node status | |||||
| λHu in VP | 0.74 (0.63,0.84) | 2.66 | 64.4 (48.8,78.1) | 79.2 (65.0,89.5) | 72.0 (61.8,80.9) |
DECT, Dual-energy computed tomography; OTSCC, Oral tongue squamous cell carcinoma; AUC, area under curves; CI, confidential interval; λHu, slope of the spectral Hounsfield unit curve; nIC, normalized iodine concentration; VP, venous phase.