Table 2.
Cytokines | AUC | Clinical malaria | Febrile controls | P-value | Sensitivity | Specificity | Cut off (pg/ml) | P-value | AUC | Sensitivity | Specificity | Cut off (pg/ml) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IL-1β | 0.78 | 0.91 | 0.64 | <32.6 | *** | 0.77 | 0.65 | 0.78 | >31.09 | ** | |||||||||||
IL-1RA | 0.75 | 0.52 | 0.88 | <2623 | ** | 0.76 | 0.83 | 0.67 | >1717 | ** | |||||||||||
IL-7 | 0.69 | 0.61 | 0.67 | <118.6 | * | 0.92 | 0.61 | 1.00 | >118.6 | **** | |||||||||||
IL-12 | 0.74 | 0.61 | 0.79 | <88.5 | ** | 0.75 | 0.65 | 0.78 | >46.7 | ** | |||||||||||
Chemokines | AUC | Sensitivity | Specificity | Cut off (pg/ml) | P-value | AUC | Sensitivity | Specificity | Cut off (pg/ml) | P-value | |||||||||||
CCL4 | 0.9 | 0.7 | 0.91 | <282.9 | **** | 0.79 | 0.91 | 0.67 | >81 | *** | |||||||||||
CCL5 | 0.96 | 0.88 | 0.96 | <275.5 | **** | 0.82 | 0.92 | 0.71 | >103.7 | ** | |||||||||||
CXCL10 | 0.86 | 0.75 | 0.85 | <77.8 | **** | 0.82 | 0.75 | 0.89 | >26.51 | *** |
*p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.