Table 5. Comparison of Background PAHs of IQOS (THS 2.2) Tobacco Stick to the Deliveries in the Emissions and 3R4F Reference Cigarette Smoke^a.

	Goujon et al.59 (Supporting Information Table S9)			Schaller et al.38 (Supporting Information Tables I and II)
	IQOS tobacco background PAH (ng/stick)			deliveries in emission/smoke HCI (ng of stick/ng of 3R4F cigarette)
sample	benzo[a]pyrene	pyrene	benzo[a]anthracene	benzo[a]pyrene	pyrene	benzo[a]anthracene
FR1	16.6	82.1	22.5	1.02	8.01	2.64
A	118.8	1381.7	347	9.10	185.65	45.66
B	56.9	243	91.2	4.34	25.26	13.33
C	<0.06	12.5	<0.05	0.35	4.50	1.02
D	48.4	568.7	138.9	3.97	63.30	20.52
E	<0.06	18.1	<0.05	0.55	4.71	1.09
3R4F				15.0	79.3	27.2

^aFRI: THS 2.2 regular blend of air cured, bright flue-cured and aromatic oriental (sun-cured) tobaccos, same as FR1 monitor blend in Schaller et al.³⁸ A: Aromatic fire-cured tobacco, same as AR1 in Schaller et al.³⁸ B: Flue-cured bright tobacco, same as FC5 in Schaller et al.³⁸ C: Flue-cured bright tobacco, same as FC6 in Schaller et al.³⁸ D – Blend of flue-cured and aromatic fire cured tobaccos, same as BL1 in Schaller et al.³⁸ E: Blend of flue-cured and aromatic oriental sun-cured tobaccos, same as BL11 in Schaller et al.³⁸ 3R4F: University of Kentucky reference cigarette, blend of flue-cured, air-cured (Burley and Maryland), oriental (sun-cured) and reconstituted tobaccos. HCI: Health Canada intense smoking regimen. PAHs:Polycyclic aromatic hydrocarbons. Data from both studies were from Supporting Information except 3R4F data, which was in main article of Schaller et al.³⁸