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. 2022 Jul 6;10(7):e004487. doi: 10.1136/jitc-2022-004487

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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Dynamic changes in serum CEA and circulating NPY/SEPT9/WIF1 DNA methylation of 4 CRLM patients. Bev, bevacizumab; CEA, carcinoembryonic antigen; chemo, chemotherapy; CRLM, colorectal cancer liver metastases; ICI, immune checkpoint inhibitor; meth-cfDNA, circulating cell-free DNA methylation; pCR, pathological complete response.