Table 1.

Marker AQUA scores by clinicopathologic variable

	Cohort 1 (N=379)							Cohort 2 (N=247)
Marker	CD11b		CD68		HLA-DR		N	CD11b		CD68		HLA-DR		N
Age
<65	29,798	p=0.23	3672	p=0.75	17,699	p=0.04	157	17,334	p=0.27	13,224	p=0.92	7215	p=0.70	115
>65	32,793		3720		16,052		211	18,075		1415		8180		132
Gender
Male	33,100	p=0.04	3720	p=0.84	17,231	p=0.76	173	17,999	p=0.28	1420	p=0.13	8049	p=0.42	196
Female	29,870		3672		17,086		199	16,557		1140		7842		31
Histology
ADC	32,987	p=0.0001	3840	p=0.008	17,247	p>0.99	202	18,905	p=0.0002	1505	p=0.22	8728	p=0.10	87
SCC	51,473		4766		17,288		86	28,003		1813		10,009		111
Other	36,230		3683		15,053		72	20,767		1253		7764		30
Smoking
Ever smoker	32,387	p=0.09	3815	p=0.05	16,836	p=0.83	296	17,897	p=0.77	1422	p=0.72	8160	p=0.62	183
Never smoker	28,103		3135		17,228		44	19,449		1390		8485		19
Stage
I–II	32,527	p=0.74	3797	p=0.59	17,482	p=0.16	279	19,763	p=0.97	1591	p=0.95	10,483	p=0.82	136
III–IV	31,667		3537		17,057		72	22,453		1749		9524		87

ADC, adenocarcinomas; SCC, squamous cell carcinomas.