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. 2022 Jul 6;10(7):e004698. doi: 10.1136/jitc-2022-004698

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

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Correlations of lung intratumor bacterial burden with tumor cells’ function. (A) Correlation of host genes with bacterial burden in tumor cells (Spearman’s rank correlation, R=0.7 cut-off shown in dotted red line). (B) Correlation between host CTNNB1 expression and bacterial burden in tumor cells (Spearman’s rank correlation, 95% CI shown in gray). (C) Representative images of immunohistochemistry staining of β-catenin in tumor regions with known low or high bacterial burden. (D) Ingenuity pathway analysis of genes correlated with bacterial burden in tumor cells.