Table 2.
Mechanisms of pancreatic exocrine insufficiency in celiac disease
No.
|
|
1 | Impaired secretion of cholecystokinin and secretin from the diseased small bowel mucosa |
2 | Reduced amino acid uptake in the small bowel, which subsequently leads to reduction in precursors for synthesis of pancreatic enzymes |
3 | Morphologic alterations in pancreatic parenchyma secondary to protein malnutrition |