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. 2022 Jun 28;28(24):2680–2688. doi: 10.3748/wjg.v28.i24.2680

Table 2.

Mechanisms of pancreatic exocrine insufficiency in celiac disease

No.

1 Impaired secretion of cholecystokinin and secretin from the diseased small bowel mucosa
2 Reduced amino acid uptake in the small bowel, which subsequently leads to reduction in precursors for synthesis of pancreatic enzymes
3 Morphologic alterations in pancreatic parenchyma secondary to protein malnutrition