Table 5.
Intraoperative and postoperative details of patients with colorectal anastomotic leakage (minor vs major)
|
|
Minor CAL, n = 7
|
Major CAL, n = 18
|
P
value
|
| Type of anastomosis, n (%) | 0.52 | ||
| Intrabdominal | 3 (42.8) | 9 (50.0) | |
| Pelvic | 4 (57.2) | 9 (50.0) | |
| Covering stoma, n (%) | 1 (14.3) | 1 (5.6) | 0.47 |
| Abdominal pain | |||
| POD3 | 1.86 | 1.94 | 0.08 |
| POD4 | 1.57 | 2.13 | 0.04 |
| POD5 | 1.86 | 1.92 | 0.03 |
| Clinical condition | |||
| POD3 | 1 | 1.25 | 0.07 |
| POD4 | 1.14 | 1.47 | 0.13 |
| POD5 | 1.29 | 1.58 | 0.02 |
| CRP levels in mg/L | |||
| POD3 | 178.35 | 221.02 | 0.28 |
| POD4 | 146.30 | 226.01 | 0.13 |
| POD5 | 107.64 | 251.45 | 0.01 |
| CLP levels in μg/mL | |||
| POD3 | 2.75 | 12.99 | < 0.001 |
| POD4 | 3.34 | 10.60 | 0.01 |
| POD5 | 2.52 | 10.96 | 0.004 |
| CAL diagnosis in d, median | 8 | 5.5 | 0.07 |
| Diagnostic method, n (%) | 0.12 | ||
| Clinical | 0 (0) | 7 (38.9) | |
| Abdominopelvic CT | 7 (100) | 11 (61.1) | |
| CAL management, n (%) | < 0.001 | ||
| Drainage | NA | 2 (11.1) | |
| Reoperation | 16 (88.9) | ||
| LOHS in d, mean ± SD | 28.0 ± 17.0 | 22.4 ± 12.9 | 0.38 |
CAL: Colorectal anastomotic leakage; POD: Postoperative day; CRP: C-reactive protein; CLP: Calprotectin; CT: Computed tomography; LOHS: Length of hospital stay; NA: Not applicable.