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. 2022 Jun 17;7(26):22601–22612. doi: 10.1021/acsomega.2c01924

Figure 4.

Figure 4

JPRED4 results for the C-terminal regions of four SQSs. The codes are H = helix, B = buried, bold font = residues in the catalytic domain, cyan = polar residues, and yellow = non-polar residues. The numbers indicate the reliability of the prediction (9 is best). (a) AfSQS (primarily the C-terminal end of the catalytic domain). (b) AfSQS (polar and TM helical regions). (c) C. albicans SQS (C-terminal end of the catalytic domain and polar and TM helical regions). (d) Human SQS (C-terminal end of the catalytic domain and TM helical regions). (e) T. cruzi SQS (C-terminal end of the catalytic domain and TM helical regions). The abbreviations are Jnet = final secondary structure prediction; jhmm = Jnet hmm profile prediction; jpssm = Jnet PSIBLAST pssm profile prediction; Jnet_25 = Jnet prediction of burial, less than 25% solvent accessibility; Jnet_5 = Jnet prediction of burial, less than 5% exposure; Jnet_0 = Jnet prediction of burial, 0% exposure; and Jnet Rel = Jnet reliability of prediction accuracy, ranges from 0 to 9, bigger is better.