Figure 6.

Proposed structural arrangement of the polar and non-polar (trans-membrane) helices in AfSQS based on JPRED4, HeliQuest, and RoseTTAFold results. (a) AfSQS model based on JPRED4 and HeliQuest results. (b) AfSQS model based on RoseTTAFold prediction, illustrated as an electrostatic charge surface computed using the PyMOL program. Blue = positively charged region, red = negatively charged region, and white = neutral (hydrophobic residues) region. Four other models are shown in Figure S2. (c) Error estimates in Ångström units for the model in panel (b) computed in the RoseTTAFold program.