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Polarity, hydrophobicity, and hydrophobic moments for the two C-terminal helices in human squalene epoxidase and a structural model for binding to a cell membrane. (a) HsSQLE (PDB ID 6C6P). (b) HeliQuest results for the penultimate (yellow) helix. (c) HeliQuest results for the terminal (cyan) helix. (d) Charged residues present in the two C-terminal helices. (e) Proposed model for membrane-binding based on rotations of the C-terminal helices.
