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. 2022 Jun 22;7(26):22421–22439. doi: 10.1021/acsomega.2c01570

Table 2. Substrate Scope for the Ultrasonic-Assisted Synthesis of 2-Phenylimidazo[1,2-a]pyridin-3-yl)cyclohex-2-enones Derivatives 4(a-o)a.

3.1.

a

Reaction conditions: 2-aminopyridine derivatives (1 mmol) 1(a-b), pertinent acetophenone (1 mmol) 2(a-g), dimedone (1 mmol) (3), and a catalytic amount (20 mol %) of I2 was irradiated for 1 h in the presence of water. Reactants 2(a-g) and (3) were added to the reaction mixture only after the disappearance of the reactant 1(a-b).

b

Isolated yield.