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. 2022 Jun 1;55(13):1785–1795. doi: 10.1021/acs.accounts.2c00093

Figure 1.

Figure 1

Precision nanoparticle assembly guided by protein cages. (a) TEM reconstruction of triangulation number T = 3 BMV–gold hybrid VLPs. (b) Transmission optical images of VLP and (c) BMV crystals. (d) Optical spectra of VLPs in crystal and solution. (e) Assembly mechanism and (f) microscopy characterization of binary ferritin crystals loaded with NPs. (g) Monitoring the nucleation and growth of gold clusters inside cross-linked apoferritin crystals. (h,i) Schematic images of magnetoferritin crystals. (j) Face-centered cubic (fcc) crystals formed by AuNPs and enzyme-loaded ferritin cages. (k) Mesoporous silica templated by (apo)ferritin crystals. Panels a–d reproduced with permission from ref (34). Copyright 2006 National Academy of Sciences. Panels e and f reproduced with permission from ref (35). Copyright 2016 American Chemical Society. Panel g reproduced with permission from ref (39). Published 2017 by Springer Nature Ltd. Panel j reproduced with permission from ref (44). Published 2019 by American Chemical Society. Panel k reproduced with permission from ref (45). Published 2021 by John Wiley & Sons.