Table 1.
Baseline demographic characteristics
| Sequence | Fasting study (n = 40) | Fed study (n = 51) | Total | P |
|---|---|---|---|---|
| Age(years) | 28.1 ± 7.7 | 31.0 ± 9.0 | 29.7 ± 8.5 | 0.11 |
| Male/Female | 30/10 | 38/13 | 62/23 | 0.96 |
| Height(cm) | 169.0 ± 9.1 | 169.7 ± 7.5 | 169.4 ± 8.2 | 0.69 |
| Weight(kg) | 63.4 ± 8.9 | 64.4 ± 8.2 | 64.0 ± 8.5 | 0.58 |
| BMI(kg/m2) | 22.1 ± 1.9 | 22.3 ± 2.0 | 22.2 ± 1.9 | 0.63 |
| PR(beats/min) | 74.7 ± 9.7 | 75.1 ± 11.5 | 74.9 ± 10.7 | 0.86 |
| SBP(mmHg) | 121.2 ± 10.9 | 121.7 ± 12.2 | 121.5 ± 11.6 | 0.84 |
| DBP(mmHg) | 72.5 ± 7.5 | 73.0 ± 7.7 | 72.7 ± 7.6 | 0.76 |
Notes: T, test formulation, compound lisinopril tablet (lisinopril /amlodipine besylate 10 mg /5 mg); R, reference formulation, Lisonorm® (lisinopril /amlodipine besylate 10 mg /5 mg); P-values were determined by independent t test
Abbreviation: BMI Body mass index, PR Pulse rate, SBP Systolic blood pressure, DBP Diastolic blood pressure