Table 2.
Multiple linear regression analysis modelling PIM and PPO on functional disability measured using the WHODAS total score (n= 410, final model after variable selection)
| Reg. coeff. B | SE | 95%-CI for B | Std. coeff. Beta | p-value | |
|---|---|---|---|---|---|
| No. of PIM | 2.65 | 0.57 | 1.53; 3.76 | 0.20 | < 0.001 |
| No. of PPO | 1.49 | 0.64 | 0.24; 2.74 | 0.10 | 0.020 |
| ISAR | 5.27 | 1.01 | 3.28; 7.25 | 0.24 | < 0.001 |
| Multimorbiditya | 0.84 | 0.29 | 0.26; 1.41 | 0.13 | 0.004 |
| No. of hospital stays in 6 m | 2.42 | 0.81 | 0.82; 4.01 | 0.13 | 0.003 |
| Gender, female | 6.55 | 1.82 | 2.96; 10.13 | 0.31 | < 0.001 |
| Living independently | -7.30 | 3.05 | -13.30; -1.30 | -0.35 | 0.017 |
| Quality of information: good | -9.67 | 3.25 | -16.06; -3.27 | -0.46 | 0.003 |
WHODAS World Health Organization Disability Assessment Schedule 2 (with 0 points indicating no and 100 points indicating maximal functional disability); Reg. coeff. B Regression coefficient B; SE Standard error; CI Confidence interval; Std. coeff. Beta Standard coefficient Beta; PIM Potentially inappropriate medication; PPO Potential prescribing omission; ISAR Identification of Seniors at Risk Screening Tool. a: Multimorbidity as measured by the outcome-orientated multimorbidity score “Activities of daily life” (ADL) of Tooth et al [32].