Table 2.

Multivariate analysis of the relationship between ALP levels and poor 3-month prognosis in AIS patients with preserved renal function

Variable	Crude OR(95%CI)	P value	Model I OR(95%CI)	P value	Model II OR(95%CI)	P value
ALP, per 10 unit increase	1.06(1.02 ~ 1.11)	0.003	1.06(1.02 ~ 1.11)	0.007	1.04(1.01 ~ 1.09)	0.041
ALP quintile
Q1	1.27(0.82 ~ 1.97)	0.276	1.26 (0.81 ~ 1.96)	0.313	1.84(1.07 ~ 3.16)	0.028
Q2	1.17(0.76 ~ 1.82)	0.472	1.21 (0.78 ~ 1.89)	0.396	2.11(1.23 ~ 3.63)	0.007
Q3	1.32(0.87 ~ 2.02)	0.196	1.33 (0.86 ~ 2.05)	0.197	2.13(1.25 ~ 3.60)	0.005
Q4	Reference	-	Reference	-	Reference
Q5	1.80(1.2 ~ 2.71)	0.005	1.81 (1.19 ~ 2.75)	0.005	2.21(1.32 ~ 3.73)	0.003
Trend test		0.171		0.183		0.762

Notes: Crude adjust none; Model I adjusted for age, sex; Model II adjusted for model I plus smoking, drinking, prior stroke, pneumonia during hospitalization, NIHSS score at admission, BMI, serum creatinine, eGFR; hypertension, atrial fibrillation, diabetes mellitus, ALT and leukocyte count

Abbreviations: ALP Alkaline phosphatase, eGFR estimated glomerular filtration rate, OR Odds ratios, CI Confidence interval, Q Quintile

Q1: < 58.8 U/L, Q2: 58.8–69.5 U/L, Q3: 69.6–81.6 U/L, Q4: 81.7–97.5 U/L, Q5: ≥ 97.6 U/L