Table 4.

Threshold effect analysis of ALP levels and poor 3-month prognosis in patients with AIS with preserved renal function

Outcome	OR(95%CI)	P value
One-line linear regression model, per 10 unit increase	1.04(1.01,1.09)	0.041
Two-piecewise linear regression mode
ALP level < 90 U/L, per 10 unit increase	0.99 (0.87,1.12)	0.857
ALP level ≥ 90U/L, per 10 unit increase	1.57(1.27,1.93)	< 0.001
Likelihood Ratio test	0.001

Notes: adjusted variables included age, sex, smoking, drinking, prior stroke, NIHSS score at admission, pneumonia during hospitalization, BMI, serum creatinine, eGFR; hypertension, atrial fibrillation, diabetes mellitus, ALT, leukocyte count

Abbreviations: ALP Alkaline phosphatase, eGFR estimated glomerular filtration rate, OR Odds ratios, CI Confidence interval, Q Quintile