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. 2022 Jul 6;26:203. doi: 10.1186/s13054-022-04068-z

Fig. 4.

Fig. 4

Relative abundance (RA) is depicted, comparing BALF culture positivity for selected pathogens with their identified diagnostic threshold. For each pathogen, sensitivity, specificity, positive predictive value (PPV), negative predictive value and area under the curve (AUC) are given with BALF conventional culture as the primary reference point and the identified 16s sequencing diagnostic relative abundance cut-off as the predictor. Values given with 95% binomial confidence intervals