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. 2022 Jun 14;8(2):veac054. doi: 10.1093/ve/veac054

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© The Author(s) 2022. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Regional variations in average pairwise sequence similarity (green/ top x-axis parameter) and GC content (blue/ bottom horizontal X-axis parameter) across coronavirus genomes. The plotted values indicate the pairwise sequence similarity and GC proportions within a moving 40-nucleotide window. Also indicated are the locations of the main genes (above each graph), transcriptional regulatory sequences (TRDs; in purple/ top stripes beneath gene boxes), identified break-point locations (in mustard/ beneath TRSB locations), potential recombination hotspots (in red/ Y-axis bright stripes through graphs) and potential recombination cold-spots (in blue/ Y-axis cold stripes through graphs).