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. 2022 Feb 2;2:803482. doi: 10.3389/fragi.2021.803482

FIGURE 3.

FIGURE 3

Adipocyte PU.1 Deficiency Protects Mice Against Age-Associated Obesity and Insulin Resistance. (A) Body weight (BW) and body composition of 10 months old male AdipoqCre-PU.1fl/fl mice (N = 6) and the control littermate PU.1fl/fl mice (N = 6). (B) For glucose tolerance test, 10 months old male mice (N = 7 vs. 5) were fasted overnight and injected with glucose (2 g/kg body weight). Blood glucose was then measured. (C) For insulin tolerance test, 1 year old male mice (N = 8 vs. 7) were fasted for 4-hr and injected with insulin (1.0 IU/kg body weight). Blood glucose was measured afterwards. *p < 0.05.