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. 2022 Feb 2;2:803482. doi: 10.3389/fragi.2021.803482

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Copyright © 2022 Chen, De Angulo, Guo, More, Ochsner, Lopez, Saul, Pang, Sun, McKenna and Tong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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RNA-sequencing Analysis of Gene Expression Changes in the aPU.1KO Mice. (A) Volcano plot showing gene expression changes in adipocytes isolated from the gonadal adipose tissue, with key genes of interest highlighted in yellow. (B) Gene ontology analysis of differentially expressed genes (p < 0.01) showing highly enriched pathways. The false discovery rate (FDR) is used for multiple hypothesis testing, with a standard cutoff of FDR<0.05 for significant pathway enrichment.