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. 2022 Feb 2;2:803482. doi: 10.3389/fragi.2021.803482

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Copyright © 2022 Chen, De Angulo, Guo, More, Ochsner, Lopez, Saul, Pang, Sun, McKenna and Tong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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3T3-L1 Adipogenic Differentiation Consensome. The mouse 3T3-L1 adipogenesis transcriptomic consensome ranks mouse genes based on their discovery rates across five independent, publicly archived 3T3-L1 adipogenesis transcriptomic datasets. Hypergeometric test odds ratio and associated p-value are indicated in each panel. (A) Validation of the 3T3-L1 adipogenesis consensome against the GSEA adipogenesis Hallmark gene set. (B) Over-representation of aPU.1KO-induced LZ50 genes among 3T3-ADIPICTs. (C) Over-representation of aPU.1KO-repressed LZ50 genes among 3T3-ADIPRCTs. (D) Correlation between aPU.1KO log FC and adipogenesis log mean FC.