TABLE 10.
Comparison of mean laboratory data (CBC, Hematology) between groups.
| Laboratory tests | Duration (Days) | Mean ( ± SD) | p value | |
|---|---|---|---|---|
| Uthever (N = 31) | Placebo (N = 31) | |||
| Hemoglobin (g/dl) | Baseline | 13.32 ± 1.65 | 13.28 ± 1.86 | 0.92 |
| 60 | 13.05 ± 1.68 | 13.32 ± 1.97 | — | |
| Mean diff (Baseline –Day 60) (p value) | −0.27 ± 0.66 (0.03) | 0.04 ± 1.03 (0.83) | 0.16 | |
| Hematocrit—PCV (%)Total | Baseline | 40.78 ± 4.37 | 39.40 ± 8.05 | 0.40 |
| 60 | 39.73 ± 4.36 | 40.85 ± 5.06 | — | |
| Mean diff (Baseline –Day 60) (p value) | −1.05 ± 2.03 (0.00) | 1.46 ± 7.26 (0.27) | 0.06 | |
| Total Leukocyte Count-WBC Total Count (/cmm) | Baseline | 6745.16 ± 1650.62 | 6612.90 ± 1289.64 | 0.72 |
| 60 | 6296.77 ± 1813.01 | 6490.32 ± 1359.25 | — | |
| Mean diff (Baseline –Day 60) (p value) | −448.39 ± 1662.50 (0.14) | −122.58 ± 899.89 (0.45) | 0.34 | |
| Neutrophils (%) | Baseline | 55.88 ± 7.87 | 53.09 ± 9.66 | 0.21 |
| 60 | 56.41 ± 8.15 | 55.14 ± 9.45 | — | |
| Mean diff (Baseline –Day 60) (p value) | 0.53 ± 7.46 (0.69) | 2.05 ± 6.86 (0.10) | 0.40 | |
| Absolute Neutrophils (/cmm) | Baseline | 3682.93 ± 1439.17 | 4185.51 ± 4267.12 | 0.53 |
| 60 | 4698.02 ± 5771.45 | 3635.80 ± 1205.23 | — | |
| Mean diff (Baseline –Day 60) (p value) | 1015.09 ± 5672.56 (0.32) | −549.72 ± 4396.63 (0.49) | 0.22 | |
| Lymphocytes (%) | Baseline | 33.79 ± 6.12 | 35.36 ± 6.89 | 0.34 |
| 60 | 34.61 ± 6.71 | 35.45 ± 9.51 | — | |
| Mean diff (Baseline –Day 60) (p value) | 0.82 ± 7.39 (0.54) | 0.08 ± 6.70 (0.94) | 0.68 | |
| Monocytes (%) | Baseline | 5.82 ± 1.77 | 5.91 ± 1.93 | 0.84 |
| 60 | 4.67 ± 1.49 | 4.87 ± 1.51 | — | |
| Mean diff (Baseline –Day 60) (p value) | −1.15 ± 1.72 (0.00) | −1.03 ± 1.55 (0.00) | 0.77 | |
| Basophils (%) | Baseline | 0.00 ± 0.00 | 0.01 ± 0.03 | 0.06 |
| 60 | 0.01 ± 0.02 | 0.01 ± 0.03 | — | |
| Mean diff (Baseline –Day 60) (p value) | 0.01 ± 0.02 (0.00) | 0.00 ± 0.05 (1.0) | 0.30 | |
| Eosinophils (%) | Baseline | 4.27 ± 4.47 | 4.60 ± 2.94 | 0.73 |
| 60 | 4.19 ± 3.43 | 4.53 ± 3.12 | — | |
| Mean diff (Baseline –Day 60) (p value) | −0.09 ± 1.79 (0.78) | −0.07 ± 1.49 (0.79) | 0.96 | |
| Platelet Count (/cmm) | Baseline | 268141.94 ± 89517.44 | 276096.77 ± 75638.77 | 0.70 |
| 60 | 272806.45 ± 81622.88 | 265764.52 ± 87540.73 | — | |
| Mean diff (Baseline –Day 60) (p value) | 4664.52 ± 47631.74 (0.58) | −10332.26 ± 58404.87 (0.33) | 0.27 | |
| Red blood cell count (mil/cmm) | Baseline | 4.66 ± 0.58 | 4.59 ± 0.57 | 0.63 |
| 60 | 4.64 ± 0.61 | 4.58 ± 0.55 | — | |
| Mean diff (Baseline –Day 60) (p value) | −0.02 ± 0.24 (0.64) | −0.00 ± 0.36 (1.0) | 0.79 | |
| Prothrombin time (seconds) | Baseline | 3.72 ± 5.22 | 4.89 ± 5.42 | 0.39 |
| 60 | 3.82 ± 4.94 | 4.92 ± 6.43 | 0.39 | |
| Mean diff (Baseline –Day 60) (p value) | 0.10 ± 4.76 (0.90) | 0.02 ± 5.51 (0.98) | 0.95 | |
| Activated Partial Thromboplastin Time (seconds) | Baseline | 29.61 ± 3.36 | 28.91 ± 3.01 | 0.39 |
| 60 | 29.81 ± 3.64 | 30.22 ± 3.20 | — | |
| Mean diff (Baseline –Day 60) (p value) | 0.20 ± 3.55 (0.75) | 1.32 ± 3.03 (0.02) | 0.18 | |
By Student “t” test p > 0.05 was considered not significant.