TABLE 12.
Comparison of mean laboratory data (RFT) between groups.
| Laboratory tests | Duration (Days) | Mean ( ± SD) | p value | |
|---|---|---|---|---|
| Uthever (N = 31) | Placebo (N = 31) | |||
| Glomerular Filtration Rate (ml/min/1.73sqm) | Baseline | 94.26 ± 16.42 | 92.23 ± 21.25 | 0.67 |
| 60 | 92.71 ± 16.56 | 90.52 ± 17.67 | — | |
| Mean diff (Baseline –Day 60) (p value) | −1.55 ± 13.15 (0.51) | −1.72 ± 10.85 (0.38) | 0.95 | |
| Urea (mg/dl) | Baseline | 18.35 ± 4.63 | 20.52 ± 6.28 | 0.12 |
| 60 | 17.79 ± 5.37 | 20.30 ± 7.06 | — | |
| Mean diff (Baseline –Day 60) (p value) | −0.56 ± 5.87 (0.59) | −0.22 ± 5.24 (0.81) | 0.81 | |
| Blood Urea Nitrogen (mg/dl) | Baseline | 8.58 ± 2.16 | 9.59 ± 2.93 | 0.12 |
| 60 | 8.37 ± 2.50 | 9.44 ± 3.34 | — | |
| Mean diff (Baseline –Day 60) (p value) | −0.21 ± 2.68 (0.66) | −0.15 ± 2.53 (0.74) | 0.92 | |
| Serum Creatinine (mg/dl) | Baseline | 0.82 ± 0.15 | 0.86 ± 0.24 | 0.43 |
| 60 | 0.83 ± 0.14 | 0.86 ± 0.22 | — | |
| Mean diff (Baseline –Day 60) (p value) | 0.01 ± 0.11 (0.61) | 0.01 ± 0.08 (0.49) | 1.0 | |
| Uric Acid (mg/dl) | Baseline | 4.85 ± 1.60 | 4.86 ± 1.36 | 0.97 |
| 60 | 4.60 ± 1.23 | 4.63 ± 1.33 | — | |
| Mean diff (Baseline –Day 60) (p value) | −0.25 ± 0.80 (0.09) | −0.24 ± 0.57 (0.02) | 0.95 | |
| Serum Sodium (mmol/L) | Baseline | 141.35 ± 2.03 | 140.58 ± 3.82 | 0.32 |
| 60 | 139.60 ± 6.84 | 140.19 ± 2.65 | — | |
| Mean diff (Baseline –Day 60) (p value) | −1.75 ± 6.73 (0.15) | −0.39 ± 2.35 (0.36) | 0.29 | |
| Serum Chloride (mmol/L) | Baseline | 102.51 ± 2.16 | 101.63 ± 3.64 | 0.25 |
| 60 | 102.77 ± 2.53 | 101.36 ± 3.16 | — | |
| Mean diff (Baseline –Day 60) (p value) | 0.26 ± 1.87 (0.44) | −0.27 ± 2.11 (0.48) | 0.29 | |
By Student “t” Test p > 0.05 was considered not significant.