Table 2.
Association between sleep disorder-related variables and stroke.
| Variables | Model 1 | P | Model 2 | P | Model 3 | P |
|---|---|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | OR (95% CI) | ||||
| Sleep duration | ||||||
| <6 h | 2.21 (1.42–3.45) | 0.001 | 2.07 (1.28–3.35) | 0.005 | 1.95 (1.19–3.19) | 0.006 |
| 6–7 h | Ref | Ref | Ref | |||
| 7–8 h | 0.91 (0.60–1.39) | 0.650 | 1.01 (0.68–1.50) | 0.953 | 1.09 (0.73–1.63) | 0.657 |
| ≥8 h | 1.56 (1.05–2.34) | 0.030 | 1.25 (0.82–1.90) | 0.294 | 1.31 (0.86–1.99) | 0.199 |
| Sleep disorder | ||||||
| No | Ref | Ref | Ref | |||
| Yes | 2.57 (1.69–3.92) | <.001 | 2.33 (1.41–3.84) | 0.002 | 1.66 (1.03–2.69) | 0.031 |
| Time required to fall asleep | 1.01 (1.01–1.02) | <.001 | 1.01 (1.01–1.02) | 0.002 | 1.01 (1.01–1.01) | 0.046 |
| Frequency of sleep deprivation | ||||||
| Never | Ref | Ref | Ref | |||
| One time a month | 0.58 (0.37–0.92) | 0.023 | 0.89 (0.57–1.41) | 0.613 | 0.83 (0.51–1.35) | 0.438 |
| 2–4 times a month | 0.73 (0.53–1.01) | 0.050 | 1.38 (0.98–1.94) | 0.067 | 1.25 (0.88–1.79) | 0.198 |
| 5–15 times a month | 0.47 (0.28–0.78) | 0.005 | 0.97 (0.57–1.66) | 0.913 | 0.80 (0.45–1.42) | 0.420 |
| 16–30 times a month | 1.35 (0.86–2.11) | 0.186 | 2.47 (1.45–4.19) | 0.002 | 1.90 (1.06–3.40) | 0.024 |
| Frequency of early-morning wakefulness | ||||||
| Never | Ref | Ref | Ref | |||
| One time a month | 0.93 (0.61–1.40) | 0.702 | 0.95 (0.63–1.44) | 0.818 | 0.92 (0.61–1.38) | 0.677 |
| 2–4 times a month | 1.19 (0.82–1.73) | 0.349 | 1.22 (0.79–1.88) | 0.356 | 1.06 (0.69–1.65) | 0.775 |
| 5–15 times a month | 1.45 (0.93–2.27) | 0.101 | 1.36 (0.85–2.17) | 0.200 | 1.14 (0.68–1.92) | 0.603 |
| 16–30 times a month | 3.07 (2.03–4.67) | <.001 | 2.53 (1.56–4.09) | 0.001 | 2.07 (1.24–3.46) | 0.004 |
| Frequency of midnight wakefulness | ||||||
| Never | Ref | Ref | Ref | |||
| One time a month | 1.03 (0.68–1.57) | 0.874 | 1.14 (0.74–1.76) | 0.545 | 1.07 (0.71–1.60) | 0.741 |
| 2–4 times a month | 1.12 (0.78–1.60) | 0.521 | 1.15 (0.78–1.70) | 0.479 | 0.98 (0.67–1.44) | 0.905 |
| 5–15 times a month | 1.50 (1.10–2.07) | 0.014 | 1.49 (1.04–2.12) | 0.030 | 1.22 (0.82–1.80) | 0.309 |
| 16–30 times a month | 2.70 (1.71–4.25) | <.001 | 2.34 (1.34–4.10) | 0.004 | 1.78 (1.01–3.18) | 0.043 |
OR – odds ratio; CI – confidence interval; Ref – reference. Model 1: unadjusted model; Model 2: adjustment of age, gender, BMI, marital status, family PIR, and education level; Model 3: adjustment of age, gender, BMI, marital status, race, education level, family PIR, waist circumference, hypertension, CHF, CHD, angina pectoris, heart attack, platelet count, diabetes, beta-blockers, and antidepressants.