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A decrease in GEM-induced liver injury and hepatotoxicity by UA administration in vivo. Treatment with GEM coupled with or without UA in MIA PaCa-2 GEMR-bearing xenograft mice. Blood samples were collected for analysis of (A) GOT, (B) GPT, (C) BUN, and (D) creatinine. Data are presented as the mean ± S.E.M. (n = 8). *p < 0.05 vs. Control group and $p < 0.05 vs. GEM group.
