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PRODH overexpression sensitized TNBC tumor cells to clinical therapeutic drugs. (a) Wild-type HS578T, PRODH-overexpressing, and vector control cells were treated with clinical therapeutic agents, including (a) lipodox (0–1 μg/mL) and (b) palbociclib (0.05–5 μM) for 4 days. The cell growth number was calculated, and the results revealed that inhibition of cell viability was only observed in the PRODH-overexpressing cells.
