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. 2022 Jul 7;13:3921. doi: 10.1038/s41467-022-30763-0

Fig. 5. Direct infection of 129S1 mice with VOCs that harbor the N501Y mutation.

Fig. 5

A 18-week-old 129S1 mice were infected with 104 PFU of MA-SARS-CoV-2, B.1.1.7, or B.1.351 (n = 10/group). B Whole lungs and nasal turbinates were harvested from n = 3/group at 3 DPI for virus titration by plaque assay. Bars represent means; error bars represent SEM. Dotted line indicates limit of detection (LOD) = 66.67 PFU/ml. Source data are provided as a Source Data file.