Fig. 8. Post-vaccination or convalescent human sera neutralize both WT- and N501Y/H655Y MA-SARS-CoV-2 viruses.
Post-vaccination or post-infection human sera were analyzed for virus neutralization by in vitro microneutralization assays using 450TCID50 of either WT-SARS-CoV-2 (USA-WA1/2020) or MA-SARS-CoV-2 and the ID50 (inhibition) values were calculated and compared. Each symbol represents ID50 value calculated for a human serum sample [negative (n = 4) versus weak (n = 8), moderate (n = 10), or strong positive (n = 11)].Sera from sero-negative individuals were used as negative control for the experiment. Dotted line (LOD). Two-sided Mann–Whitney U test was performed to calculate the statistical significance (p) between different groups. The box-whisker plots show all minimum to maximum data points, with respective medians and interquartile range. Source data are provided as a Source Data file.