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. 2022 Jun 22;3:881543. doi: 10.3389/fpain.2022.881543

Table 1.

Baseline characteristics of the sample.

Variables Overall Phasic protocol Tonic protocol
N = 521 Summation,
N = 151
No summation, N = 411 Summation, N = 111 No summation, N = 411
Age 48.08 (11.12) 46.93 (10.65) 48.54 (11.42) 49.36 (11.62) 47.73 (11.11)
Female 45/52 (87%) 12/15 (80%) 33/37 (89%) 10/11 (91%) 35/41 (85%)
BMI 28.18 (6.86) 30.97 (7.56) 27.05 (6.32) 26.95 (6.11) 28.51 (7.08)
Duration of fibromyalgia 10.38 (8.60) 7.70 (7.06) 11.47 (9.00) 11.45 (10.93) 10.10 (8.00)
Patients in low dose opioids 5/52 (9.6%) 1/15 (6.7%) 4/37 (11%) 1/11 (9.1%) 4/41 (9.8%)
CPM −0.89 (1.33) −1.27 (1.08) −0.74 (1.41) −0.74 (1.31) −0.93 (1.35)
Vas pain (0–10) 6.00 (1.77) 5.91 (1.79) 6.04 (1.78) 5.16 (1.60) 6.22 (1.76)
Vas anxiety (0–10) 4.41 (2.64) 3.91 (2.60) 4.61 (2.66) 4.64 (2.53) 4.35 (2.69)
Vas depression (0–10) 3.84 (2.91) 3.33 (2.90) 4.05 (2.92) 2.97 (2.98) 4.08 (2.88)
Vas sleep (0–10) 6.04 (2.57) 5.01 (2.79) 6.45 (2.39) 5.95 (2.91) 6.06 (2.51)
Vas stress (0–10) 5.41 (2.93) 4.55 (3.30) 5.76 (2.73) 4.45 (3.18) 5.67 (2.84)
BPI pain intensity 5.38 (1.58) 5.28 (1.80) 5.41 (1.51) 5.09 (1.54) 5.45 (1.61)
BPI pain interference 5.46 (2.16) 5.15 (2.02) 5.58 (2.23) 4.70 (1.81) 5.66 (2.22)
BPI number of locations with pain (0–72) 12.21 (8.13) 10.53 (7.48) 12.89 (8.39) 11.27 (7.21) 12.46 (8.43)
FIQR (0–100) 55.67 (18.62) 53.81 (22.56) 56.42 (17.07) 49.36 (19.50) 57.36 (18.26)
QOLD (16–112) 68.52 (14.20) 71.60 (19.01) 67.27 (11.81) 70.55 (16.35) 67.98 (13.74)
BDI (0–63) 16.87 (9.18) 16.60 (11.38) 16.97 (8.30) 18.36 (8.03) 16.46 (9.51)
PROMIS anxiety (0–5) 2.66 (0.95) 2.50 (0.90) 2.73 (0.98) 2.66 (1.16) 2.66 (0.91)
PROMIS fatigue (0–5) 3.89 (0.77) 3.38 (0.75) 4.10 (0.69) 3.89 (0.88) 3.90 (0.75)
PROMIS pain (0–5) 3.61 (0.97) 3.43 (1.04) 3.68 (0.95) 3.16 (1.01) 3.73 (0.94)
PSQI (0–21) 12.08 (4.52) 11.20 (4.68) 12.43 (4.46) 11.73 (5.42) 12.17 (4.31)

1Mean(SD); n/N (%). QOLS, Quality of Life scale; PROMIS, Patient-Reported Outcomes Measurement Information System; VAS, Visual Analog Scale; PSQI, Pittsburgh Sleep Quality Index; FIQR, Revised Fibromyalgia Impact Questionnaire; BPI, Beck's Depression Inventory; BDI, Brief Depression Inventory. *Races reported as white vs. non-white and Hispanic vs. non-Hispanic, collapsed to increase statistical power. Presence indicates any increase in pain with continuous or repetitive stimuli; absence indicates no increase or decrease in pain with continuous or repetitive stimuli.