Table 1.
Demographic, clinical presentation, and treatment of 6 patients with positive culture of Sporothrix schenckii
| Demographic | Clinical presentation | Treatment | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
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| Patient | Age (year)/sex | Ocular presentation | Site of lesion | Duration (d) | Predisposing factors | HPE results | Treatment (oral) | Duration (months) | Outcome | ||
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| Symptoms | Signs | Exposure to cats | Others | ||||||||
| Case 1 | 61/male | RE purulent discharge, eyelid swelling | Granulomatous conjunctivitis | Conjunctiva | 7 | No | Gardener | Granulomatous inflammation | Itraconazole 200 mg bd | 6 | Resolved with symblepharon |
| Case 2 | 24/female | LE lobulated lesions at palpebral conjunctiva | Granulomatous conjunctivitis | Conjunctiva | 2 | Yes | Granulomatous inflammation | Itraconazole 100 mg od for 2 weeks then increased to 200 mg bd for 2 months | 2 | New lesion at lower palpebral conjunctiva when on lower dose and resolved with higher dose | |
| Case 3 | 39/female | LE lobulated lesions at palpebral conjunctiva | Granulomatous conjunctivitis | Conjunctiva | 21 | Yes | Granulomatous inflammation | Itraconazole 200 mg bd | 2 | Resolved | |
| Case 4 | 17/male | LE lower eyelid skin swelling | Lid and granulomatous conjunctivitis | Eyelid and conjunctiva | 21 | Yes | Granulomatous inflammation | Itraconazole 200 mg bd | 6 | Resolved with skin scarring | |
| Case 5 | 56/female | RE discomfort, discharge | Lower palpebral conjunctiva nodules mimicking concretion | Conjunctiva | 5 | Yes | Granulomatous inflammation | Itraconazole 200 mg bd | 4 | Resolved with symblepharon | |
| Case 6 | 22/female | RE redness, foreign body sensation | Granulomatous conjunctivitis | Conjunctiva | 21 | Yes | Granulomatous inflammation | Itraconazole 200 mg bd | 5 | Resolved | |
RE=Right eye, LE=Left eye, HPE=Histopathological examination, bd=Twice daily