Table 2. - Epidemiological data and clinical characteristics.
| Author | Case Report | Epidemiology | Clinical Characteristics |
|---|---|---|---|
| Wu et al. ( 10 ) | Case report of a 3-month-old newborn with remarkable tumor growth in 4 days without previous trauma. | 70% of cases are located in the maxilla, followed by the cranial, mandibular and cerebral regions. | Fast growing, pigmented, firm, sessile tumor with malignant potential. |
| Moreu et al. ( 3 ) | Clinical research with 11 patients aged (months) ranging from 0 to 5 months and mean age of 3.18 months. | Prediction for the head and neck area, especially in the jaw bone. | Painless, sessile, pigmented (black or blue) and non-ulcerated lesion. |
| Unsal; Yançin ( 9 ) | A 6-month-old male child with increased mandibular volume. | It affects more the head and neck region. And it predominantly affects the maxilla (70 to 80%), skull (10%), mandible (6%) and brain (4%). In addition to the predominance in babies. | It presents as a rapidly growing, locally destructive, painless, immobile, black, brown, or blue pigmented swelling. |
| Pontes et al. ( 5 ) | Literature review. | Greater predominance in gnathic bones and slightly affect males (1.32: 1). | More satisfactory prognosis in younger patients, due to the size of the pathology and less chance of metastasis. |
| Santos et al. ( 2 ) | Anterior maxillary growth in a 6-month-old girl | Prevalence in gnathic bones (maxilla) in males and occurs in the first year of life, especially in the first months. | Rapid growth, invasive and causing deformities. Possibly malignant transformation and bone metastasis. |
| Soles et al. ( 8 ) | Literature review. | Greater predominance in craniofacial bones (maxillary) and male predilection. | Firm, lobulated change, well-defined mass, bluish-black hue. In addition to showing rapid growth and local infiltration into adjacent tissues. |
| Ren et al. ( 4 ) | Literature review. | Higher prevalence in cranial bones, observed in men and women, in addition to being diagnosed in the first years of life. | Progressive, asymptomatic growth and firm edema, with an intact epithelial surface. |
| Tiwari; Yadav ( 6 ) | 3-month-old girl with intraoral swelling and progressive growth and firm consistency. | More commonly in the craniofacial region, mainly the maxillary bone, followed by the skull, mandible and predilection in children under 1 year of age. | Pigmented and benign neoplasm, with high potential for rapid growth and locally destructive. |
| Ebel et al. ( 1 ) | Case report of a 4-month-old boy with MNTI in the skull and 2-week rapid growth | Greater involvement in the maxillary region, followed by the cranial region. | Rapid development, without symptoms, pigmentary and invasive edema. |
| Mengide et al. ( 11 ) | Extra-axial growth in the skull of an 8-year-old boy complaining of headache for about 3 months. | The most common location of the tumor is the craniofacial region, although other regions are described. Mainly in patients under 1 year of age. | Solid and painless lesion, in addition to being pigmented and is a neoplasm causing deformity in regions of appearance. |
The table summarizes some clinical cases with the epidemiological and clinical characteristics of MNTI reported by the corresponding authors.
Source: Done by the authors.