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. Author manuscript; available in PMC: 2022 Jul 7.
Published in final edited form as: Clin Cancer Res. 2021 Jun 4;27(17):4726–4736. doi: 10.1158/1078-0432.CCR-20-4622

Figure 3.

Figure 3

Flow cytometric analysis of B cells in LTCR (blue) versus all other patients (red). (A) Log of median values with error bars indicating 75th and 25th percentiles. Non-LTCR tended to have both more B cells than LTCR as well as less of a Day 30 reduction in B cells following rituximab. Flow gating strategy for these experiments can be found in Supplementary Figure 2. (C) Box whisker plots of quantified B cells on Day 30. When compared to partial responders, complete responders tended to have fewer B cells. (D) Receiver operator characteristic curves constructed for B cells number as a classifier to distinguish LTCR from all others. Area under the curve values are calculated for Days 0 and 30.