Fig 3. MaxHiC enriches for interactions between regulatory regions, eQTL-target pairs and known enhancer-promoter pairs.

a) Fraction of regulatory elements in the significant interactions identified by the four models. b) Enrichment of cell line specific chromatin pairs, chromatin state pairs, and eQTL pairs that overlapped with both ends of the significant interactions identified by the six models at fragment size 10kb. The enrichment is calculated by dividing the fraction of features overlapping both ends of the significant interactions identified by each model by the fraction of features overlapping both ends of all interactions (see methods).