Table 1. Physiological and metabolic parameters at 2 weeks after treatment with heme-binding protein 1 (Hebp1).
Variable | Control | Streptozotocin-induced diabetic mice | ||
---|---|---|---|---|
Phosphate-buffered saline | Hebp1 | |||
1 μg | 5 μg | |||
Body weight (g) | 31.4±0.4 | 24±0.3* | 24.4±0.4* | 23.9±0.3* |
Fasting glucose (mg/dL) | 102.4±1.8 | 553±18.1* | 563.4±18.2* | 541.2±17.6* |
Postprandial glucose (mg/dL) | 168.8±12.1 | 598.2±1.8* | 599.8±0.2* | 597.8±2.2* |
Mean systolic blood pressure (mm Hg) | 102.0±1.6 | 105.8±2.4 | 101.4±2.8 | 102.2±2.4 |
Values are presented as mean±standard error of the mean for n=5 animals per group.
*p<0.05 vs. control group.