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. 2022 Jun 23;50(12):6618–6638. doi: 10.1093/nar/gkac519

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© The Author(s) 2022. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — Roles of the N-PAZ lobe. (A) The bilobed structure is essential for high target specificity and mismatch recognition. (B) The lack of the N-PAZ lobe impairs the target specificity and mismatch recognition.