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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Thorax. 2021 Jul 16;76(12):1186–1192. doi: 10.1136/thoraxjnl-2020-215918

Table 3:

Association between PBL-TL and FVC trends in UCSF SSc-ILD patients using Generalized Linear Mixed Models

UCSF Cohort
(n=72, 203 PFTs)		 Telomere Length (Per 1000 base pair decrease)
Coefficient 95%CI P-value
Unadjusted model −0.134 −0.235– −0.024 0.012
Adjusted model* −0.136 −0.239– −0.040 0.012
*

Adjusted by age, male sex, body mass index (BMI), ethnicity, smoking status, anti-topoisomerase antibodies, and classification of disease.

PBL, peripheral blood leukocyte; TL, telomere length; FVC, forced vital capacity; UCSF, University of California San Francisco; SSc-ILD, systemic sclerosis associated interstitial lung disease; CI, confidence interval.