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. 2022 Jun 3;37(3):444–454. doi: 10.3803/EnM.2021.1341

Table 4.

Comparisons of the Differences in Blood Glucose Levels at the Time of Transition and the Length of Hospital Stay by Group

Variable Difference in glucose levels before PSM (n=165)
Difference in glucose levels after PSM (n=108)
Length of hospital stay (n=144)
Β±SE P value Β±SE P value Β±SE P value
Univariable
Groupa –79.92±15.34 <0.001b –84.83±18.76 <0.001b –1.13±0.56 0.046b
Multivariable
Groupa –84.61±22.88 <0.001b –84.59±25.76 0.001b –1.20±0.53 0.027b
Age, yr –0.29±0.49 0.562 –0.86±0.62 0.169 –0.00±0.02 0.837
BMI, kg/m2 3.19±2.02 0.117 1.54±2.37 0.519 - -
Classification (DKA)c –27.80±22.91 0.227 –35.76±27.97 0.204 0.52±0.78 0.505
Classification (HHS)c –27.09±23.40 0.249 –33.38±28.48 0.244 1.64±0.81 0.043b
Classification (HHS with ketoacidosis)c –14.423±22.26 0.518 –21.64±27.85 0.439 0.38±0.75 0.613
Dose of basal insulin, U –0.66±1.53 0.669 0.38±1.71 0.825 - -
Duration of CIII, hr –0.27±0.41 0.511 –0.42±0.44 0.353 0.02±0.01 0.056
Glucose level immediately before CIII discontinuation, mg/dL –0.90±0.19 <0.001b –0.96±0.23 <0.001b - -
Duration of DM, yr 0.63±0.86 0.467 1.85±1.07 0.085 –0.03±0.03 0.390
Precipitating factor –27.92±17.33 0.109 –22.10±20.55 0.285 2.11±0.63 0.001b
OHA (metformin) 3.79±22.97 0.869 –0.95±27.07 0.972 - -
OHA (sulfonylurea) 9.41±23.13 0.685 14.73±28.66 0.609 - -
OHA (DPP4 inhibitor) –1.55±23.70 0.948 –24.65±28.47 0.389 - -
OHA (SGLT2 inhibitor) 3.71±40.16 0.927 21.15±45.66 0.645 - -

B, β coefficient; SE, standard error; PSM, propensity score matching; BMI, body mass index; DKA, diabetic ketoacidosis; HHS, hyperosmolar hyperglycemic state; CIII, continuous intravenous insulin infusion; DM, diabetes mellitus; OHA, oral hypoglycemic agent; DPP4, dipeptidyl peptidase 4; SGLT2, sodium/glucose cotransporter 2.

a

Early vs. delayed basal insulin group;

b

Values are statistically significant (P<0.05) by linear regression analyses;

c

Data are compared to the category of severe hyperglycemia that did not satisfy the criteria for either DKA or HHS.