Skip to main content
. Author manuscript; available in PMC: 2023 Jul 6.
Published in final edited form as: Neuron. 2022 May 3;110(13):2110–2123.e4. doi: 10.1016/j.neuron.2022.04.012

Figure 5. An Nav1.6 specific channel blocker affects the OFFsA and not the bSbC.

Figure 5.

(A, B) Example action potentials waveforms and corresponding dV/dt plots in synaptic blocker (SB) conditions and with 10 nM 49TTX for the OFFsA (A) and bSbC (B). OFFsA is green for SB and black for 49TTX, bSbC is purple for SB and gray for 49TTX.

(C) Firing rate as a function of injected current. Shaded region is SEM across cells (OFFsA N = 8, bSbC N = 5). Statistics are calculated using the non-parametric permutation test (Methods); * p < 0.05, - not significant.

(D) Plots of action potential max slope over the local membrane voltage. Shaded region is SEM across cells (see Methods, OFFsA N=9, bSbC N=5). *** p < 0.001, ** p < 0.01, * p < 0.05, - not significant.

See also Figure S4.