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. Author manuscript; available in PMC: 2023 Jul 6.
Published in final edited form as: Neuron. 2022 May 3;110(13):2110–2123.e4. doi: 10.1016/j.neuron.2022.04.012

Figure 8. Blockade of NaV1.6 pushes the OFFsA into depolarization block for negative contrasts.

Figure 8.

(A) Example traces of OFFsA RGCs to 100% negative contrast steps in dynamic clamp recordings at four different concentrations of 49TTX.

(B, C, D) Spike count during the contrast step conductance (B, p = 0.008, ANOVA), membrane voltage (C, p = 0.76, ANOVA), and input resistance (D, p = 0.32, ANOVA) as a function of 49TTX concentration.