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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Med Care. 2022 Jun 4;60(8):570–578. doi: 10.1097/MLR.0000000000001742

Table 1.

Pre-planned analyses

Analysis Rationale Model
I.0 Prediction of utilization without psychosocial vital signs Demographics, prior utilization, and multimorbidity predict future utilization. ED / Hospitalizations predicted by all features except psychosocial vital signs.
I.1 All psychosocial vital signs to predict utilization Psychosocial factors are known to exacerbate chronic illnesses. ED / Hospitalizations predicted by all psychosocial vital signs and other features ; compare to I.0
I.2 Diabetes morbidity and financial insecurity, housing insecurity Patient costs for caring for diabetes have increased, and diabetes requires consistent places to store medication, leading to diabetes exacerbations Predict ED / hospitalizations with housing insecurity and financial insecurity
I.3 ASCVD and Chronic stress Chronic stress increases the risk of ASCVD outcomes Predict ED/hospitalizations in patients with chronic stress and ASCVD
I.4 Depression and Social isolation Social isolation and mood disorders generate more exacerbations together Predict ED/hospitalizations in patients with social isolation and depression
I.5 Substance Use and housing insecurity The combination of substance use and housing insecurity worsens outcomes Preduct ED/hospitalizations in patietnts with substance use and housing insecurity
*

ASCVD = Atherosclerotic Cardiovascular Disease; ED=Emergency Department