Table 3.

Aneurysm formation in diabetic ApoE^−/− x NOX5^ki/ki animals and their respective WT controls at 20 weeks of study.

	Animals with aneurysms		Average expansion
	Absolute n with/without	%	%
Non-diabetic ApoE−/− x WT	1/21	4.8%	178%
Non-diabetic ApoE−/− x eNOX5ki/ki	0/32	0.0%	n/a
Diabetic ApoE−/− x WT	3/24	12.5%	144 ± 3%
Diabetic ApoE−/− x eNOX5ki/ki	9/32	28.1%*	155 ± 8%

Data are expressed as the number of animals with aneurysms present, compared to the total number of animals assessed for aneurysm formation. Average % expansion as compared to normal vessel width measured above and below the aneurysm (where normal vessel = 100%); n for average expansion: nondiabetic ApoE^−/− x WT = 1, Diabetic ApoE^−/− x WT = 3, Diabetic ApoE^−/− x eNOX5^ki/ki = 8.

Overall significant in a non-parametric multiple comparison (Kruskal Wallis test).

*p < 0.01 Diabetic ApoE^−/− x eNOX5^ki/ki versus non-diabetic ApoE^−/− x eNOX5^ki/ki.