Table 2.
Correlations between LDH-C4 protein expressions and clinical characteristics in LUAD patients.
| Clinicopathological features | Total case size(n = 92) | LDH-C4 low(n = 16) | LDH-C4 high(n = 76) | χ2 value | p-value | ||
|---|---|---|---|---|---|---|---|
| Gender | 0.704 | 0.402 | |||||
| Male | 49 | 7 | 42 | ||||
| Female | 43 | 9 | 34 | ||||
| Age (years) | 2.216 | 0.137 | |||||
| >60 | 42 | 10 | 32 | ||||
| ≤60 | 50 | 6 | 44 | ||||
| T stage | 0.000 | 1.000 | |||||
| T1–T2 | 69 | 12 | 57 | ||||
| T3–T4 | 23 | 4 | 19 | ||||
| Lymphatic metastasis | 0.654 | 0.419 | |||||
| N0–N1 | 53 | 10 | 43 | ||||
| N1–N2 | 22 | 6 | 16 | ||||
| Nx | 17 | ||||||
| Clinical stage | 0.222 | 0.638 | |||||
| Stage I+II | 43 | 10 | 33 | ||||
| Stage III+IV | 32 | 6 | 26 | ||||
| EGFR mutation | 0.103 | 0.749 | |||||
| Negative | 73 | 13 | 60 | ||||
| Positive | 14 | 2 | 11 | ||||
| Unclear information | 5 | ||||||
| ALK mutation | 0.085 | 0.771 | |||||
| Negative | 77 | 13 | 64 | ||||
| Positive | 15 | 3 | 12 |
The final score of LDH-C4 expression is the product of score and intensity.