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. 2022 Jul 7;13(7):586. doi: 10.1038/s41419-022-05035-w

Fig. 2. Familial PMF with CHST15 mutation exhibits activation of immune/inflammation/extracellular matrix signals in PBMNCs.

Fig. 2

A Heatmap shows hierarchical clustering of expression profiles of 4 differentially expressed CHST15 target genes in familial PMF (red:upregulation;blue:downregulation). Microarray assay of genes with >2.0-fold upregulation or downregulation. B Familial essential thrombocythemia (ET) genes expression profiles. Heatmap shows hierarchical clustering of profiles of 12 differentially expressed genes. C Genes expression profiles both in familial PMF and in familial ET.