Table 1.
Demographic characteristics at baseline of the zoledronic acid + eldecalcitol and zoledronic acid groups; univariate analysis.
| Variables, median (Q1, Q3) | ZOL + ELD group (n = 51) | ZOL group (n = 47) | P-value |
|---|---|---|---|
| Age, yr | 75 (72, 81) | 75 (70, 82) | 0.550 |
| Female, n (%) | 48 (92.3) | 44 (93.6) | 1.000 |
| Body mass index, kg/m2 | 22.4 (19.9, 24.5) | 21.9 (20.4, 23.7) | 0.784 |
| Cr-eGFR, mL/min/1.73m2 | 68.5 (59.8, 77.0) | 68.2 (59.6, 76.7) | 0.862 |
| Value of serum calcium, mg/dL | 9.5 (9.3, 9.8) | 9.6 (9.3, 9.8) | 0.839 |
| Presence of vertebral fractures, n (%) | 25 (49.0) | 25 (53.2) | 0.692 |
| Lumbar spine T-score | −2.6 (−3.3, −1.8) | −2.5 (−3.0, −1.8) | 0.370 |
| Total hip T-score | −2.3 (−2.9, −2.0) | −2.5 (−2.9, −2.1) | 0.722 |
| Femoral neck T-score | −2.8 (−3.3, −1.8) | −2.8 (−3.3, −2.3) | 0.709 |
| P1NP, ng/mL | 68.3 (53.4, 86.0) | 69.0 (48.6, 80.7) | 0.768 |
| TRACP-5b, mU/dL | 573 (445, 667) | 511 (416, 678) | 0.211 |
ZOL, zoledronic acid; ELD, eldecalcitol; Q1, 25th percentile; Q3, 75th percentile; Cr-eGFR, estimated glomerular filtration rate calculated by creatinine; P1NP, N-terminal propeptide of type I procollagen; TRACP-5b, tartrate-resistant acid phosphatase-5b.